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The CYLD protein is involved in a rare genetic disorder (familial cylindromatosis). Researchers at the Large Scale Biology Laboratory show that a dysfunction of this protein that regulates the formation of cilia on the surface of cells can lead to a cancerous transformation of these cells types. With this work, they identify a new mechanism that may be involved in tumor development in these patients.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.