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Publications of the CMBA

Published on 17 January 2023

Gori A, Boucherle B, Rey A, Rome M, Barette C, Soleilhac E, Philouze C, Fauvarque MO, Fuzzati N and Peuchmaur M
Investigation of chemical composition and biological activities of Ajuga pyramidalis - Isolation of iridoids and phenylethanoid glycosides.
Metabolites, 2023, 13(1): 128


Journet A, Barette C, Aubry L, Soleilhac E and Fauvarque MO
Identification of chemicals breaking the USP8 interaction with its endocytic substrate CHMP1B.
SLAS Discovery, 2022, 27: 395-404

Mameri H, Buhagiar-Labarchède G, Fontaine G, Corcelle C, Barette C, Onclercq-Delic R, Beauvineau C, Mahuteau-Betzer F and Amor-Guéret M
Cytidine deaminase deficiency in tumor cells is associated with sensitivity to a naphthol derivative and a decrease in oncometabolite levels.
Cellular and Molecular Life Sciences, 2022, 79(8): 465

Saier L, Ribeiro J, Daunizeau T, Houssin A, Ichim G, Barette C, Bouazza L and Peyruchaud O
Blockade of platelet CysLT1R receptor with zafirlukast counteracts platelet protumoral action and prevents breast cancer metastasis to bone and lung.
International Journal of Molecular Sciences, 2022, 23(20): 12221


Faouzi A, Arnaud A, Bancet A, Barette C, Preto J, Do CV, Jordheim LP, Bousfiha Z, Binh Nguyen TT, Verrière M, Farce A, Fauvarque MO, Barret R and Lomberget T
Combretastatin A-4 sulfur-containing heterocyclic derivatives: Synthesis, antiproliferative activities and molecular docking studies.
European Journal of Medicinal Chemistry, 2021, 215: 113275

Giacosa S, Pilet C, Séraudie I, Guyon L, Wallez Y, Roelants C, Battail C, Evrard B, Chalmel F, Barette C, Soleilhac E, Fauvarque MO, Franquet Q, Sarrazin C, Peilleron N, Fiard G, Long JA, Descotes JL, Cochet C. and Filhol O
Cooperative blockade of CK2 and ATM kinases drives apoptosis in VHL deficient renal carcinoma cells through ROS overproduction.
Cancers, 2021, 13(3): 576

Kobaisi F, Sulpice E, Barette C, Fayyad N, Fauvarque MO, Badran B, Fayyad-Kazan M, Fayyad-Kazan H, Gidrol X and Rachidi W
Isoconazole and clemizole hydrochloride partially reverse the Xeroderma pigmentosum C phenotype.
International Journal of Molecular Sciences, 2021, 22(15): 8156

Rioux B, Pinon A, Gamond A, Martin F, Laurent A, Champavier Y, Barette C, Liagre B, Fagnère C, Sol V and Pouget C
Synthesis and biological evaluation of chalcone-polyamine conjugates as novel vectorized agents in colorectal and prostate cancer chemotherapy.
European Journal of Medical Chemistry, 2021, 222: 113586

Soleilhac E, Comte M, da Costa A, Barette C, Picoli C, Mortier M, Aubry L, Mouthon F, Fauvarque MO and Charvériat M
Quantitative automated assays in living cells to screen for inhibitors of hemichannel function.
SLAS Discovery, 2021, 26(3): 420-427


Ramirez-Rios S, Michallet S, Peris L, Barette C, Rabat C, Feng Y, Fauvarque MO, Andrieux A, Sadoul K and Lafanechere L
A new quantitative cell-based assay reveals unexpected microtubule stabilizing activity of crtain kinase inhibitors, clinically approved or in the process of approval.
Frontiers in Pharmacology, 2020, 11: 543

Senarisoy M, Barette C, Lacroix F, De Bonis S, Stelter M, Hans F, Kleman JP, Fauvarque MO and Timmins J
Förster resonance energy transfer based biosensor for targeting the hNTH1-YB1 interface as a potential anticancer drug target.
ACS Chemical Biology, 2020, 15(4): 990-1003


Ngo TD, Plé S, Thomas A, Barette C, Fortuné A, Bouzidi Y, Fauvarque MO, Freita RP, de Hilário FF, Attrée I, Wong YS and Faudry E
Chimeric protein–protein interface inhibitors allow efficient inhibition of Type III secretion machinery and Pseudomonas aeruginosa virulence. ACS Infectious Diseases, 2019, 5(11): 1843-1854

Picoli C, Soleilhac E, Journet A, Barette C, Comte M, Giaume C, Mouthon F, Fauvarque MO and Charvériat M
High-Content Screening identifies new inhibitors of connexin 43 gap junctions.
Assay Drug Development Technologies, 2019, 17(5): 240-248


Conte M, Lupette J, Seddiki K, Meï C, Dolch LJ, Gros V, Barette C, Rébeillé F, Jouhet J and Maréchal E
Screening for biologically annotated drugs that trigger triacylglycerol accumulation in the diatom Phaeodactylum.
Plant Physiology, 2018, 177(2): 532-552

Cortes S, Barette C, Beroud R, De Waard M and Schaack B
Functional characterization of cell-free expressed Kv1.3 channel using a voltage-sensitive fluorescent dye.
Protein Expression and Purification, 2018, 145: 94-99

Ouarné M, Bouvard C, Boneva G, Mallet C, Ribeiro J, Desroches-Castan A, Soleilhac E, Tillet E, Peyruchaud O and Bailly S
BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer.
Journal of Experimental & Clininical Cancer Researc, 2018, 37(1): 209

Soleilhac E, Brillet-Guéguen L, Roussel V, Prudent R, Touquet B, Dass S, Aci-Sèche S, Kasam V, Barette C, Imberty A, Breton V, Vantard M, Horvath D, Botté C, Tardieux I, Roy S, Maréchal E and Lafanechère L
Specific targeting of plant and apicomplexa parasite tubulin through differential screening using in silico and assay-based approaches.
International Journal of Molecular Sciences, 2018, 19(10): Article number 3085

Wallez Y, Bouillot S, Soleilhac E, Huber P, Attrée I and Faudry E
CLIQ-BID: A method to quantify bacteria-induced damage to eukaryotic cells by automated live-imaging of bright nuclei.
Scientific Reports, 2018, 8(1): Article number 5


Basso P, Wallet P, Elsen S, Soleilhac E, Henry T, Faudry E and Attrée I
Multiple Pseudomonas species secrete exolysin-like toxins and provoke Caspase-1-dependent macrophage death.
Environmental Microbiology, 2017, 19(10):4045-4064


Do CV, Faouzi A, Barette C, Farce A, Fauvarque MO, Colomb E, Catry L, Berthier-Vergnes O, Haftek M, Barret R and Lomberget T
Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit.
Bioorganic and Medicinal Chemistry Letters, 2016, 26(1): 174-180


Barette C, Soleilhac E, Charavay C, Cochet C and Fauvarque MO
Strength and specificity of the CMBA screening platform for bioactive molecules discovery.
Medecine Sciences (Paris), 2015, 31(4): 423-431

Brodin P, DelNery E and Soleilhac E
High Content Screening in chemical biology: Overview and main challenges.
Médecine Sciences, 2015, 31(2): 187-96

Desroches-Castan A, Quelard D, Demeunynck M, Constant JF, Dong C, Keramidas M, Coll JL, Barette C, Lafanechere L and Feige JJ
A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras.
Oncotarget, 2015, 6(7): 5382-5411

Martinez A, Soleilhac E, Barette C, Prudent R, Gozzi GJ, Vassal-Stermann E, Pillet C, Pietro AD, Fauvarque MO and Lafanechere L
Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.
Current Cancer Drug Targets, 2015, 15(1): 2-13

Murie C, Barette C, Button J, Lafanechère L and Nadon R
Improving detection of rare biological events in High-Throughput Screens.
Journal of Biomolecular Screening, 2015, 20(2): 230-241


Murie C, Barette C, Lafanechère L and Nadon R
Control-Plate Regression (CPR) normalization for High-Throughput Screens with many active features.
Journal of Biomolecular Screen, 2014, 19(5): 661-671


Boussouar A, Barette C, Nadon R, Saint-Léger A, Broucqsault N, Ottaviani A, Firozhoussen A, Lu Y, Lafanechère L, Gilson E, Magdinier F and Ye J
Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.
Molecular Therapy. Nucleic Acids, 2013, 2: e116

Murie C, Barette C, Lafanechère L and Nadon R
Single assay-wide variance experimental (SAVE) design for high-throughput screening.
Bioinformatics, 2013, 29(23): 3067-3072

Prudent R, Soleilhac E, Barette C, Fauvarque MO and Lafanechère L
Phenotypic screens or one stone to kill two birds: Discover the target and its pharmacological regulator.
Médecine Sciences, 2013, 29(10): 897-905

Prudent R, Vassal-Stermann E, Nguyen CH, Mollaret M, Viallet J, Desroches-Castan A, Martinez A, Barette C, Pillet C, Valdameri G, Soleilhac E, Di Pietro A, Feige JJ, Billaud M, Florent JC and Lafanechère L
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
British Journal of Pharmacology, 2013, 168: 673–68


Camara D, Bisanz C, Barette C, Van Daele J, Human E, Barnard B, Van Der Straeten D, Stove CP, Lambert WE, Douce R, Maréchal E, Birkholtz LM, Cesbron-Delauw MF, Dumas R and Rébeillé F
Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine
Journal of Biological Chemistry, 2012, 287(26): 22367-22376

Lo E, Soleilhac E, Martinez A, Lafanechère L and Nadon R
Intensity quantile estimation and mapping-a novel algorithm for the correction of image non-uniformity bias in HCS data.
Bioinformatics, 2012, 28(20): 2632-2639

Prudent R, Vassal-Stermann E, Nguyen CH, Pillet C, Martinez A, Prunier C, Barette C, Soleilhac E, Filhol O, Beghin A, Valdameri G, Honore S, Aci-Seche S, Grierson D, Antonipillai J, Li R, Di Pietro A, Dumontet C, Braguer D, Florent JC, Knapp S, Bernard O and Lafanechere L
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth.
Cancer Research, 2012, 72(17): 4429-4439


Moucadel V, Prudent R, Sautel CF, Teillet F, Barette C, Lafanechere L, Receveur-Brechot V and Cochet C
Antitumoral activity of allosteric inhibitors of Protein kinase CK2.
Oncotarget, 2011, 2(12): 997-1010


Lopez-Ramos M, Prudent R, Moucadel V, Sautel CF, Barette C, Lafanechere L, Mouawad L, Grierson D, Schmidt F, Florent JC, Filippakopoulos P, Bullock AN, Knapp S, Reiser JB and Cochet C
New potent dual inhibitors of CK2 and Pim kinases: Discovery and structural insights.
FASEB Journal, 2010, 24(9): 3171-3185

Soleilhac E, Nadon R and Lafanechère L
High-content screening for the discovery of pharmacological compounds: Advantages, challenges and potential benefits of recent technological developments.
Expert Opinion on Drug Discovery, 2010, 5: 135-144


Hoang TM, Favier B, Valette A, Barette C, Nguyen CH, Lafanechère L, Grierson DS, Dimitrov S and Molla A
Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.
Cell Cycle, 2009, 8(5): 765-772


Prudent R, López-Ramos M, Moucadel V, Barette C, Grierson D, Mouawad L, Florent JC, Lafanechère L, Schmidt F and Cochet C
Salicylaldehyde derivatives as new protein ikinase CK2 inhibitors.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2008, 1780(12): 1412-1420

Prudent R, Moucadel V, Lopez-Ramos M, Aci S, Laudet B, Mouawad L, Barette C, Einhorn J, Einhorn C, Denis JN, Bisson G, Schmidt F, Roy S, Lafanechère L, Florent JC and Cochet C
Expanding the chemical diversity of CK2 inhibitors.
Molecular and Cellular Biochemistry, 2008, 316(1-2): 71-85


Barette C
La démarche qualité pour le criblage automatisé in Chemogénomique, des petites molécules pour explorer le vivant, édité par Maréchal E, Roy S and Lafanechère L. EDP Sciences, Grenoble Sciences, 2007, pp 81-87

Fonrose X, Ausseil F, Sans-Soleilhac E, Masson V, David B, Pouny I, Cintrat JC, Rousseau B, Barette C, Massiot G and Lafanechère L
Parthenolide inhibits tubulin carboxypeptidase activity.
Cancer Research, 2007, 67(7): 3371-3378

Laudet B, Barette C, Dulery V, Renaudet O, Dumy P, Metz A, Prudent R, Deshiere A, Dideberg O, Filhol O and Cochet C
Structure-based design of small peptide inhibitors of protein-kinase CK2 subunit interaction.
Biochemical Journal, 2007, 408(3): 363-373


Vassal E, Barette C, Fonrose X, Dupont R, Sans-Soleilhac E and Lafanechère L
Miniaturization and validation of a sensitive multi-parametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents.
Journal of Biomolecular Screening, 2006, 11: 377-389


Sans-Solheihac E, Barette C, Wieczorek S, Roy S, Maréchal E and Lafanechère L
Criblages phénotypiques et "génétique chimique directe" : une approche innovante pour la découverte de molécules bio-actives et/ou de candidats médicaments.
Spectra Analyse, 2003, 32: 33-37