Christophe Bruley EDyP Director

Yohann Couté EDyP Deputy Director

The EDyP team​ (“Study of Proteome Dynamics") develops proteomic approaches to understand the physiological and pathological functioning of complex biological systems. Our goal is to elucidate the links between proteomes, phenotypes, and pathologies, using a multidisciplinary approach that integrates biology, biochemistry, analytical sciences, and data science. Our research aims to establish proteomics as a key technology in the biomedical field.

As part of multi-omics investigations, the use of mass spectrometry-based proteomics for in-depth patient phenotyping is expected to open up new research horizons and support advances in healthcare, towards personalized medicine.​

The recognized expertise of EDyP team in the development of tailored proteomic methods is applied, in particular, to the study of the pathophysiology of lung diseases, such as idiopathic pulmonary fibrosis.

The team's research program is based on six main theme​s:

•   Study of the mechanisms controlling the initiation, progression, and exacerbation of lung fibrosis,

•    Identification and evaluation of biomarkers in clinical cohorts,

•    High-content proteomics for the analysis of complex biological systems,

•    Epigenetic regulation of gene expression,

•    Data science for proteomics,

•    Development of new measurement technologies for biology and health.