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Biomicrotechnology and functional genomics (Biomics)

Published on 29 April 2024
Head of Biomics

Xavier Gidrol
Phone: 33 (0)4 38 78 97 96

Biography of Xavier Gidrol
  Éric Sulpice
Deputy Director
Phone: 33 (0)4 38 78 25 9​
Julie Bourget
Phone: 33 (0)4 38 78 22 36 and 66 71
Fax: 33 (0)4 38 78 59 17

Biosciences and bioengineering for health laboratory​
17 avenue des Martyrs
38 054 Grenoble


Cell functions are influenced by the genetic program of cells but also through stimuli from the microenvironment: neighboring cells, extracellular matrix, soluble signal from stroma, physical constraints, etc. To discriminate the respective part of genetic and microenvironment on cell fate, it is necessary to control them at three dimensional scale (3D).

We use the potential of microfabrication and microfluidic to characterize genetic determinants which control the balance between proliferation and differentiation in the course of development and carcinogenesis in pancreas and skin. More specifically, we used large scale biology approaches (RNAi-based high content and throughput screening) on human cells grown in 3D (organoids, tumoroids, spheroids and organoids on chip) to characterize new biomarkers and therapeutic targets in oncology.

The team

Key words

Prostate cancer, breast cancer, interference RNA, 3D organoids, organ on chip, 3D bioprinting