Presentation
The automated screening of chemical compound collections (chemical libraries) allows the discovery of active molecules on biological systems (bio-active molecules).
The screening of thousands of compounds requires computer facilities suitable for both
backup and
analysis of chemical libraries and screening results and for the exploitation of information relative to target-molecule interactions. The software
TAMIS (
Tool to
Analyse and
Manage
Informations of
Screening) has been developed to respond to these requirements.
TAMIS software consists of two modules:
-
Chemical libraries management module: this module allows to manage the information relative to chemical compounds, plates, suppliers …
-
Screening management and analysis module:
• management of experiment information
• storage and analysis of primary and secondary screening results (or validation screenings)
• management of multiparametric screenings.
Demonstration
• Chemical libraries management
module
• Module de gestion et d'analyse de criblages
•
Project creation
•
Data import
• Screening analysis:
•
Threshold analysis
•
Singularities detection
•
Screen results management
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Contact
If you are interested in the software TAMIS, thank you to
send an email.
Download
TAMIS software will soon be distributed as
open source software under the terms of the
CeCILL-C licence.
References
TAMIS software: Tool to Analyse and Manage Informations of Screening
Charavay C, Wieczorek S, Segard S, Barette C, Soleilhac E, Maréchal E, Lafanechère L and Roy S
Institut de Recherches en Technologies et Sciences pour le Vivant (iRTSV), CEA, CNRS
© CEA, CNRS 2010