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We demonstrate the value of using a cocktail of protein kinase inhibitors against a form of kidney cancer. For this, they assessed the impact of combinations of molecules on the viability of kidney cancer cells grown as spheroids, or organ cultures of tumors. The synergistic benefit of two molecules allowed to file a patent.
Thesis presented June 11, 2008 by Xavier Fonrose. PhD thesis available in Intranet as a pdf file.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.