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Using chemogenomic screening, researchers in our laboratory are identifying a new target candidate for the treatment of metastatic clear cell renal cell carcinoma (mccRCC). The combination of inhibitors targets two protein kinases that are essential in the mechanisms of cell survival and DNA repair: protein kinases CK2 and ATM.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.